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  • Writer's pictureDr. Yuksel Yurttas

Short Stature: Causes, Diagnosis, and Treatment Options

Are you or your child struggling with short stature? The feeling of being shorter than average compared to same-age individuals is something that many families can relate to. But what causes this condition and what options are available for treatment? In this article, we're going to take a deep dive into the world of short stature. From genetic factors to growth issues, we'll explore the medical explanations behind why some people are shorter than others. And most importantly, we will discover the treatment options available to help individuals reach their full potential height. Don't let short stature hold you or your child back. Join us as we unravel the mysteries of this condition and learn how to overcome it

height measurement examination

Short stature diagnosis

Diagnosing short stature requires a thorough examination and evaluation of various factors, including the child's weight, height, head size, medical and family history, and growth patterns. This can be done through regular pediatrician checkups or if the condition is suspected from birth.

To determine the underlying cause of short stature, the pediatrician may conduct various investigations, such as:

  • An x-ray to check for bone growth issues

  • A test for insulin tolerance to check for deficiency of insulin-like growth factor-1 (IGF-1)

  • Screening for thyroid-stimulating hormone to detect hypothyroidism

  • Tests to check for inflammatory bowel illness, anemia, or issues with the liver and kidneys

  • Enzyme deficiency conditions through urine tests

  • Celiac disease through Immunoglobulin A and tissue transglutaminase testing

  • Other imaging tests like an x-ray of the bones and the head or an MRI can identify issues with the pituitary gland or hypothalamus.

  • Bone marrow or skin biopsies can also diagnose diseases linked to short height.

It's important to note that the pediatrician will also inquire about the family's medical history and the child's growth patterns, such as the family's average height, any history of disease, the onset of puberty, and the child's diet. So be ready to answer questions like:

  • What is your family's average height?

  • Does your family have any history of disease?

  • When did puberty start for both parents?

  • How was the delivery of your child?

  • Is your child's growth showing any correlations?

  • What is the typical diet of your child?

With the help of these investigations, doctors can determine the underlying cause of short stature and recommend the most appropriate treatment options.

What causes short stature?

Short stature can be caused by a variety of factors, including genetics, disease, and constitutional growth delay.

Constitutional growth delay: This refers to children who mature more slowly than their peers. These children may hit puberty late and be undersized for their age, but will continue to develop height long after their peers have stopped growing. Eventually, they will catch up to their peers in height by maturity.

Genetics: A child's height can be influenced by the height of their parents and grandparents. Additionally, a child's desired height is only an estimate and some children may not reach their full potential height.

Disease: Many illnesses can lead to abnormally small stature. Some of the most common causes include:

Endocrine conditions: Disruptions in hormone production can affect growth. These include lack of growth hormone (GHD), hypothyroidism, and Cushing's syndrome.

Chronic illnesses: Persistent health issues involving the pituitary gland can also impact growth. Short stature can be a side effect of childhood cancer or its treatment, as radiation to the brain may disrupt pituitary function.

Gastrointestinal conditions: Growth-impairing gastrointestinal conditions, such as celiac disease and inflammatory bowel disease, can also affect height.

Other illnesses: A variety of other illnesses, such as hypothyroidism, cardiovascular disease, renal disease, and immunological disease can also slow down growth.

Genetic conditions: Genetic disorders such as Prader-Willi syndrome, Turner syndrome, and Noonan syndrome can also cause short stature.

Bone diseases and malnutrition: Illnesses that affect bone growth, such as rickets or achondroplasia, can alter height.

Additionally, difficulties during pregnancy or malnutrition can also reduce a child's height.

Treatment of Short Stature

Short stature can be caused by a variety of factors, such as malnutrition, hormonal imbalances, or genetic conditions. The treatment regimen will depend on the underlying cause of the short stature.

For children who are experiencing malnutrition, vitamin supplements or treatments for gastrointestinal diseases may be necessary to address the issue. In cases where hormonal issues are preventing or delaying growth, treatment with growth hormone may be required. The U.S. Food and Drug Administration (FDA) has approved the use of growth hormone for the treatment of several conditions that result in short stature, including growth hormone deficiency, Prader-Willi syndrome, Noonan syndrome, Turner syndrome, kidney disease, and when a child is extremely small for their gestational age.

Growth hormone therapy involves daily injections of the hormone, which can increase adult height by up to 4 inches (10 cm) over time. This treatment can also be used in adults who are experiencing short stature.

Limb Lengthening as a Treatment for Short Stature

While growth hormone therapy can be effective for treating short stature in childhood, experts are constantly exploring new and more efficient ways to address the issue. For those who do not respond well to growth hormone therapy before the end of puberty, limb lengthening surgery may be recommended as a final treatment modality.

Limb lengthening, also known as stature lengthening surgery, is a surgical procedure that increases a person's height by lengthening their bones. The procedure utilizes the body's natural ability to regenerate new bone, making it possible to gain up to 6 cm in the tibia (lower leg) or 8 cm in the femur (upper leg) with a bilateral limb lengthening procedure. With two limb lengthening procedures, it is possible to gain up to 15 cm in height.

It's important to note that there is an age limit for limb lengthening surgery and it's not recommended for children under the age of 7 years old. This is because their bones are still growing and the surgery might affect their natural growth. Moreover, the surgery is not recommended for people over the age of 60 years old as the risk of complications is higher.

Limb lengthening surgery is considered the ultimate solution for short stature and can also be used for patients who want to be taller for cosmetic or psychological reasons. If you're considering limb lengthening surgery, it's important to consult with a specialist surgeon who can give you the best advice and guidance.

The Takeaway

If you suspect that your child's growth is being slowed, it's important to talk to your pediatrician as soon as possible. Early diagnosis and treatment can help your child reach a healthy height. Identifying the underlying cause of your child's slow growth will help you determine the appropriate course of treatment. This might include vitamin supplements, treatments for gastrointestinal diseases, or growth hormone therapy.

It's important to note that limb lengthening surgery is not recommended for children under the age of 7 years old, as their bones are still growing and the surgery may affect their natural growth.

If you're an adult interested in learning more about limb lengthening surgery, consider booking a free consultation with a specialist surgeon. This will give you a chance to discuss your options, learn more about the procedure, and determine your eligibility.

You can reach out to us via WhatsApp at +90 533 973 5289 or email us at for more information and to schedule your consultation.

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